[28] Basics of Single-cell Technologies in Cardiovascular Diseases

Question 1

What is the main focus of the review titled “Single-cell technologies to decipher cardiovascular diseases”?

Answer 1

Understanding cardiovascular diseases on a cellular level through single-cell technologies.

Question 2

What do single-cell technologies include?

Answer 2

• Single-cell RNA sequencing (scRNA-seq)
• Single-nuclei RNA sequencing

Question 3

What does scRNA-seq stand for?

Answer 3

Single-cell RNA sequencing

Question 4

How do single-cell technologies benefit cardiovascular disease research?

Answer 4

• Identify mechanistic drivers
• Diagnostic tools for risk stratification
• Individualized therapy

Question 5

What is Cellular Heterogeneity?

Answer 5

Variability among cell types crucial to cardiovascular disease pathogenesis.

Question 6

What changes in cells during disease progression?

Answer 6

Some cells become dysfunctional, altering cellular cross-talk dynamics.