[34] Cellular Responses to Myocardial Infarction (MI) Flashcards
1
Q
What gene is upregulated in fibroblasts post-MI?
A
Ckap4
2
Q
B2M - Initials
A
Beta-2 Microglobulin
3
Q
What does increased B2M from cardiomyocytes indicate post-MI?
A
Possible activation of fibroblasts
4
Q
What is the role of Plvap in endothelial cells post-MI?
A
May promote endogenous cardiac tissue repair
5
Q
Plvap - Initials
A
Plasmalemma Vesicle-Associated Protein
6
Q
EndMT - Initials
A
Endothelial-to-Mesenchymal Transition
7
Q
What happens to endothelial cells in response to MI?
A
Transient EndMT with enrichment of glycolytic genes and some mesenchymal markers.