[34] Cellular Responses to Myocardial Infarction (MI) Flashcards

1
Q

What gene is upregulated in fibroblasts post-MI?

A

Ckap4

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2
Q

B2M - Initials

A

Beta-2 Microglobulin

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3
Q

What does increased B2M from cardiomyocytes indicate post-MI?

A

Possible activation of fibroblasts

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4
Q

What is the role of Plvap in endothelial cells post-MI?

A

May promote endogenous cardiac tissue repair

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5
Q

Plvap - Initials

A

Plasmalemma Vesicle-Associated Protein

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6
Q

EndMT - Initials

A

Endothelial-to-Mesenchymal Transition

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7
Q

What happens to endothelial cells in response to MI?

A

Transient EndMT with enrichment of glycolytic genes and some mesenchymal markers.

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