[35] Single-cell Analysis in Vascular Diseases Flashcards

1
Q

scATAC-seq - Initials

A

Single-cell Assay for Transposase-Accessible Chromatin using Sequencing

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2
Q

SMC - Initials

A

Smooth Muscle Cell

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3
Q

What do immune cells in atherosclerotic plaques indicate?

A

Possible role in plaque stabilization.

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4
Q

What change do endothelial cells show under disturbed flow conditions?

A

Transition to pro-inflammatory and immune cell-like phenotypes.

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5
Q

What is observed about SMCs in atherosclerotic plaques?

A

Phenotypic switching leading to de-differentiation, migration, and transdifferentiation.

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