[35] Single-cell Analysis in Vascular Diseases Flashcards
1
Q
scATAC-seq - Initials
A
Single-cell Assay for Transposase-Accessible Chromatin using Sequencing
2
Q
SMC - Initials
A
Smooth Muscle Cell
3
Q
What do immune cells in atherosclerotic plaques indicate?
A
Possible role in plaque stabilization.
4
Q
What change do endothelial cells show under disturbed flow conditions?
A
Transition to pro-inflammatory and immune cell-like phenotypes.
5
Q
What is observed about SMCs in atherosclerotic plaques?
A
Phenotypic switching leading to de-differentiation, migration, and transdifferentiation.