[09] What is Known and What the Study Adds

Question 1

What was previously known about obesity and AF?

Answer 1

Obesity is an independent risk factor for AF, with reduced cardiac sodium channel expression as a causal mechanism.

Question 2

What does this study add?

Answer 2

• Use of DIO model
• New findings on ion channel and structural remodeling
• Therapeutic insights via mitochondrial antioxidants