35. (Para)Typhus Flashcards

1
Q

(Para/Typhus)

Erreger

A

Salmonella enterica serovar

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2
Q

(Para/Typhus)

direkte Infektion

A

Mensch zu Mensch

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2
Q

(Para/Typhus)

Infektionsweg (2)

A
  • direkte Infektion
  • indirekte Infektion
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3
Q

(Para/Typhus)

indirekte Infektion

A

fäkal-oral (kontaminierte Lebensmittel und verunreinigtes Wasser)

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4
Q

(Para/Typhus)

Salmonellen-Dauerausscheider

A

> 10 Wochen nach Erkrankung weiterhin positive Stuhlkulturen

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5
Q

(Para/Typhus)

Komplikationen (2)

A

Darmblutung und -Perforation

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6
Q

(Para/Typhus)

Prävention

A

Impfung

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7
Q

(Para/Typhus)

Impfung (2)

A
  • keine generelle Impfempfehlung
  • keine lebenslange Immunität
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8
Q

(Para/Typhus)

Stadien (3)

A
  1. incrementi (1. Krankheitswoche)
  2. fastigii (2. und 3. Krankheitswoche)
  3. decrementi
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8
Q

(Para/Typhus)

Stadium incrementi: Leitsymptome (2)

A

Reiseanamnese

+ Fieber über Tage

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9
Q

(Para/Typhus)

Stadium fastigii: Leitsymptome (3)

A
  • Kontinua-Fieber
  • Bradykardie
    (trotz Fieber)
  • Roseolen
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10
Q

(Para/Typhus)

Kontinua-Fieber: Charakteristiken (2)

A
  • geringes Ansprechen auf Antipyretika
  • i.d.R. mit Schüttelfrost
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11
Q

(Para/Typhus)

Roseolen: häufigste Lokalisation

A

meist periumbilikal

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12
Q

(Para/Typhus)

Stadium decrementi: Charakteristik

A

langsames Abklingen der Symptome

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13
Q

(Para/Typhus)

Laborentscheidung (2)

A
  • Stadium incrementi
  • Stadium fastigii
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14
Q

(Para/Typhus)

Labor der Wahl: Stadium incrementi

A

Blutkulturen

15
Q

(Para/Typhus)

Labor der Wahl: Stadium fastigii

A

Stuhlkulturen oder Serologie

16
Q

(Para/Typhus)

Therapie der Wahl

A

Antibiotika

17
Q

(Para/Typhus)

Antibiotika der Wahl Beispiel)

A

Fluorchinolonen (Ciprofloxacin)

18
Q

(Para/Typhus)

alternative Antibiotika (Grund)

A

Cephalosporine (aufgrund der zunehmenden Resistenzen)