17. Clostridioides Difficile Infektion Flashcards

1
Q

(CDI)

Erreger: Charakteristiken (2)

A
  • grampositives Stäbchen
  • obligat anaerob
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2
Q

(CDI)

Risikofaktor

A

Antibiotikagabe zur Therapie einer anderen Erkrankung

(z.B. bei HNO-Bereich oder bei Pneumonie)

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2
Q

(CDI)

Infektionsweg

A

fäkal-oral

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3
Q

(CDI)

Leitsymptome

A

Trias

  • hohes Fieber
  • Diarrhö
  • abdominalle Schmerzen
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4
Q

(CDI)

Diarrhö: Charakteristiken (2)

A
  • wässrig
  • faulig-übelriechend
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4
Q

(CDI)

abdominalle Schmerzen: Lokalisation

A

insb. in den unteren Quadranten

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5
Q

(CDI)

Labortests (2)

A

Blut- und Stuhluntersuchung

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6
Q

(CDI)

Stuhluntersuchung (2)

A
  • Screeningtest
  • Diagnosesicherung
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6
Q

(CDI)

Blutuntersuchung

A

Blutkultur

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7
Q

(CDI)

Stuhluntersuchung: Screeningtest

A

Antigentest

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8
Q

(CDI)

Stuhluntersuchung: Diagnosesicherung

A

Toxin A und B

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9
Q

(CDI)

Diagnosesicherung: Standard

A

ELISA oder PCR

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9
Q

(CDI)

Diagnosesicherung: Goldstandard

A

Zytotoxizitätstest in der Kultur

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10
Q

(CDI)

allgemeine Therapie (2)

A
  • Antibiotika, PPI und NSAR absetzen
  • Isolierung bis 2 Tage nach Abklingen der Symptome
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10
Q

(CDI)

medikamentöse Therapie der Wahl

A

Fidaxomicin p.o. für 10d

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11
Q

(CDI)

alternative Therapie der Wahl

A

Vancomycin oder Metronidazol p.o. für 10d