27. Ösophaguskarzinom Flashcards by Ian Paglione | Brainscape

Q

(Ösophaguskarzinom)

Ätiologie (2)

A

Adenokarzinom (60%)
Plattenepithelkarzinom (40%)

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Q

(Ösophaguskarzinom)

Adenokarzinom: Präkanzerose

A

Barrett-Ösophagus (Zylinderzellmetaplasie)

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Q

(Ösophaguskarzinom)

Adenokarzinom: Lokalisation

A

v.a. unteres Drittel des Ösophagus

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Q

(Ösophaguskarzinom)

Plattenepithelkarzinom: Risikofaktoren (2)

A

Alkoholabusus
Rauchen

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Q

(Ösophaguskarzinom)

Plattenepithelkarzinom: Lokalisation

A

oberhalb des unteren Drittels des Ösophagus

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Q

(Ösophaguskarzinom)

Leitsymptom

A

Dysphagie (im fortgeschrittenen Stadium)

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Q

(Ösophaguskarzinom)

Basisdiagnostik: Goldstandard

A

ÖGD

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Q

(Ösophaguskarzinom)

Staging: Goldstandard

A

Thorax- und Abdomen-CT

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Q

(Ösophaguskarzinom)

Therapiemöglichkeiten (3)

A

operative Therapie
neoadjuvante Chemotherapie
neoadjuvante Radiochemotherapie

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Q

(Ösophaguskarzinom)

operative Therapie: Verfahren (2)

A

endoskopische oder chirurgische Resektion

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Q

(Ösophaguskarzinom)

endoskopische Resektion: Indikation

A

bis T1N0M0

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Q

(Ösophaguskarzinom)

chirurgische Resektion: Indikation

A

T2-T4 oder N+M0

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Q

(Ösophaguskarzinom)

neoadjuvante Chemotherapie: Indikation

A

Adenokarzinome T3 und T4

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Q

(Ösophaguskarzinom)

neoadjuvante Chemotherapie: Schema

A

FLOT: 5-FU, Folinsäure, Oxaliplatin, Docetaxel

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Q

(Ösophaguskarzinom)

neoadjuvante Radiochemotherapie: Indikation

A

Plattenepithelkarzinom T3 und T4

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Q

(Ösophaguskarzinom)

neoadjuvante Radiochemotherapie: Schema

A

40-50 Gy (1,8-2,0 Gy pro Fraktion)