29. Kolonpolypen Flashcards

1
Q

(Kolonpolypen)

häufigste Form

A

neoplastisch (Adenom)

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2
Q

(Kolonpolypen)

Histologie (3)

A
  • tubulär
  • tubulovillös
  • villös

(je villöser desto böser)

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3
Q

(Kolonpolypen)

Bildgebung der Wahl

A

Koloskopie

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4
Q

(Kolonpolypen)

Therapie der Wahl

A

Resektion

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5
Q

(Kolonpolypen)

Resektion: Möglichkeiten (2)

A

< 5 mm: Biopsiezange

> 5 mm: elektrische Schlinge

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6
Q

(Kolonpolypen)

FAP: häufiger Befund

A

congenital hypertrophy of the retinal pigment epithelium (CHRPE)

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7
Q

(Kolonpolypen)

FAP: Sonderform

A

Gardner-Syndrom

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8
Q

(Kolonpolypen)

Gardner-Syndrom: Klinik (3)

A
  • intestinale Polypen
  • Knochentumoren
  • Weichteiltumoren
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9
Q

(Kolonpolypen)

MUTYH-assoziierte Polyposis

  1. Charakteristik
  2. Vererbung
  3. Mutation
A
  1. adenomatös
  2. rezessiv
  3. MUTYH-Gen
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10
Q

(Kolonpolypen)

FAP:

  1. Charakteristik
  2. Vererbung
  3. Mutation
A
  1. adenomatös
  2. dominant
  3. APC-Tumorsuppressor-Gen
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11
Q

(Kolonpolypen)

Peutz-Jeghers-Syndrom

  1. Charakteristik
  2. Vererbung
  3. Mutation
A
  1. hamartomatös
  2. dominant
  3. STK11-Gen
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12
Q

(Kolonpolypen)

FAP

  1. Klinik
  2. Koloskopie
  3. Risiko für KRK
  4. Therapie
A
  1. Veränderung des Stuhlgangs
  2. > 100 Polypen
  3. 100%
  4. prophylaktische Proktokolektomie
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13
Q

(Kolonpolypen)

Peutz-Jeghers-Syndrom

  1. Klinik
  2. Koloskopie
  3. Risiko für KRK
A
  1. periorale Hyperpigmentierung
  2. < 20 Polypen
  3. 40%
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14
Q

(Kolonpolypen)

MUTYH-assoziierte Polyposis

  1. Koloskopie
  2. Risiko für KRK
A
  1. > 20 Polypen
  2. 80-100%
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