180. Bovine anaplasmosis.

Question 1

Anaplasmosis of cattle Occurence?

Answer 1

Anaplasmosis of cattle

Occurrence:

• worldwide,
• more frequent on tropics

Question 2

Aetiology of Anasplasmosis?

Answer 2

Aetiology:

• A. marginale
• A. centrale
• A. ovis

Question 3

Epidemiology of Anasplasmosis?

Answer 3

Epidemiology

• Transmission: ticks, blood sucking arthropods, iatrogenic
• Natural focal infection
• Susceptibility: ruminants

Question 4

Pathogenesis?

Answer 4

Pathogenesis

• RBCs are infected
• Macrophages phagocyte the infected RBCs
• Anaemia (no haematuria)

Question 5

Clinical signs Anasplasmosis?

Answer 5

Clinical signs

• In young animals milder, in older animals more severe signs
• Fever, anorexia, anaemia (not haemolytic – no haematuria),
• jaundice (incr rate of Hb decomposition),
• hypoxia,
• abortion (consequence of anoxia)

Question 6

PM lesions?

Answer 6

PM lesions

• Haemorrhages, oedema, anaemia, jaundice; splenomegaly, enlargement of LNs
• Gall sickness (increased amount of bile)
• Urine is normal! – no haematuria!!

Question 7

Diagnosis of Anasplasmosis?

Answer 7

Diagnosis

• Epidemiology – clinical signs – PM lesions
• Detection of the agent: Giemsa (edge RBC), IF, PCR
• Serology: CFT, micro agglutination, precipitation, ELISA

Question 8

Treatment of Anasplasmosis?

Answer 8

Treatment:

• oxytetracycline
• repeated treatment can result eradication

Question 9

Prevention of anasplasmosis?

Answer 9

Prevention

• control of ticks;
• isolated keeping;
• isolation of diseased animals

Question 10

Disease of cattle caused by A.bovis?

Answer 10

Disease of cattle caused by A. bovis

• Africa, Middle East, India, America
• Replication in monocytes
• Clinical signs resemble heartwater