104. Enterotoxaemia of sheep and goats. Flashcards
1
Q
Occurence of enterotoxaemia?
A
Enterotoxemia caused by C. perfringens D (pulpy kidney disease)
• Occurrence:
- worldwide,
- common
2
Q
Ethiology of Enterotoxaemia in sheep?
A
• Etiology:
- C. perfringens D
- toxin alpha, epsilon (activated by trypsin)
3
Q
Epidemiology of Enterotoxaemia?
A
• Epidemiology:
- most frequent 6-12 month old lambs
- kids
- intensive feeding
- predisposing factors
- overeating,
- low fiber,
- high protein and carbohydrate content,
- changing the diet
4
Q
Pathogenesis of Enterotoxaemia?
A
Pathogenesis:
- slower persitaltic movement
- > toxin production (epsilon toxin)
- > activation by trypsin
- Toxin effects: permeability of the gut increased,
- endothelial damage (parenchymal organs, brain),
- kidney PM autolysis,
- glycogen content of the liver will be decreased
5
Q
Clinical signs of enterotoxaemia?
A
• Clinical signs:
- fast
- neurological signs
- abdominal pain
- diarrhea
- glucosuria
6
Q
Pathology of enterotoxaemia?
A
Pathology:
- hemorrhages
- serum in the pericardium
- abomasum inflammation
- enteritis
- pulpy kidney
7
Q
Diagnosis of enterotoxaemia?
A
Diagnosis:
- epidemiology,
- clinical signs,
- PM lesion (histology)
- o Detection of the agent: microscopy, culture
- o Detection of the toxin
- o Detection of glucose content of the urine
8
Q
Treatment?
A
Treatment
- none(hyperimmune serum)
9
Q
Prevention?
A
Prevention:
- prevent predisposing effects
- vaccination
