13th November Flashcards

1
Q

What should be used first line for sedation of an agitated patient?

A

Chlorpromazine

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2
Q

What is the management of Alzheimers disease?

A

1st line- acetylcholinesterase inhibitors such as donepezil, galantamine and rivastigmine
2nd line- NMDA receptor antagonist, memantine

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3
Q

When is memantine used in Alzheimers disease?

A

Moderate Alzheimers who are intolerant/contraindicated to have 1st line
Add on drug for moderate-severe disease
Monotherapy in severe disease

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4
Q

When is donepezil contraindicated?

A

In bradycardia

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5
Q

What is the medical management of miscarriage?

A

Mifepristone- weakens attachment to endometrial wall, softens cervix and causes uterine contractions
48 hours later- misoprostol, furthers contractions and expels uterine products

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6
Q

What is the management of incomplete miscarriage?

A

Single dose of misoprostol

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7
Q

How is termination of pregnancy done medically?

A

Mifepristone followed by vaginal administration of misoprostol

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8
Q

What are causes of nasal septal perforation?

A

Granulomatosis with polyangiitis
Cocaine Use
Nose Picking
Decongestants

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9
Q

What is Granulomatosis with Polyangiitis?

A

Autoimmune vasculitis affecting resp tract and kidneys

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10
Q

What are features of granulomatous with polyangiitis?

A

Epistaxis
Sinusitis
Nasal Crusting
Dyspnoea
Haemoptysis
Rapidly progressing glomerulonephritis
Vasculitic rash
Eye involvement

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11
Q

What is Atelectasis?

A

Collapse of part or all of the lung

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12
Q

What is a risk factor for atelectasis?

A

Anaesthesia
Prolonged bed rest with minimal position changes
Shallow breathing
Underlying lung disease

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13
Q

What are features of mycoplasma pneumoniae?

A

Flu like symptoms initially
Then dry cough

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14
Q

What are complications of mycoplasma pneumoniae?

A

Cold agglutins (IgM)- lead to haemolytic anaemia or thrombocytopenia
Erythema multiforme/nodosum
Guillain Barre Syndrome
Bullous myringitis- painful vesicles on tympanic membrane
Pericarditis
Hepatitis
Pancreatitis

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15
Q

What is the management of mycoplasma pneumoniae?

A

Doxycycline or macrolide e.g. erythromycin

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16
Q

What is Goodpastures disease?

A

Autoimmune disorder causing damage to kidneys and lungs

17
Q

What are symptoms of goodpastures

A

Haematuria
Haemoptysis
Pain on urination
Dyspnoea
Pale skin
Fatigue
Proteinuria

18
Q

What antibodies are detected in Goodpastures?

A

Anti-glomerular basement membrane antibodies

19
Q

What is the management of goodpastures?

A

Immunosuppression and plasmapheresis

20
Q

what is refeeding syndrome?

A

Combination of electrolyte balances brought on by sudden introduction of nuttrition

21
Q

What electrolyte imbalances are seen in refeeding syndrome?

A

Hypomagnesia
Hypokalaemia
Hypophosphataemia

22
Q

What findings are found with Thalassaemia major?

A

Hypochromic, microcytic anaemia
Target cells

23
Q

What laxative should be used in a aptient with an ileostomy for constipation?

A

Magnesium SulfateW

24
Q

What is the management of an arterial ulcer?

A

If no signs of infection or necrosis then hydrocolloid dressing

25
Q

What is Peutz Jegher syndrome?

A

Autosomal dominant condition
Leads to numerous polyps in GI tract

26
Q

What are features of PJS?

A

Pigmented lesions on lips, oral mucosa, face, palms and soles
Hamartomatous polyps in GI tract (often small bowel)
- can lead to SBO commonly due to intussuception

27
Q

What are risk factors for PPH?

A

Previous PPH
Porlonged labour
Polyhydraminos
Multiple pregnancy
Antepartum haemorrhage
PET
Placenta previa
Macrosomia
Em C section

28
Q

What are signs of congenital heart failure in babies?

A

Postnatal:
Heart murmur
Cyanosis
Poor feeding
Shortness of breath
Sweating
Hepatomegaly