1 January #2

Question 1

What are features of AA amyloidosis?

Answer 1

Caused by Autoimmune diseases or chronic infections

Nephrotic syndrome
Hepatomegaly
Weight loss
Fatigue/malaise

Question 2

What is the management of rosacea?

Answer 2

If flushing main symptom
- topical bromonidine gel

Mild
-topical ivermectin

Severe
-topical ivermectin and PO doxycycline

Question 3

What can be used in threatened miscarriage to prevent miscarriage?

Answer 3

Vaginal progesterone 400mg BD until week 16

Question 4

What are features of syphillis?

Answer 4

Primary
- chancre with regional lymphadenopathy

Secondary
-generalised lymphadenopathy
- snail tract lesions
-condylomata lata- wart like lesions
-rash

Tertiary syphilis
- neurosyphilis
-Aortitis
- Gumma- nodules/plaques

Question 5

What are features of Adult onset Stills Disease?

Answer 5

Fever
Joint pain
Rash
Ferritin/ESR/ CRP elevated

Treat with NSAIDS and steroids

Long term- Methotrexate

Question 6

What is the referral pathway for suspected lung cancer?

Answer 6

Refer to 2WW if
CXR suggestive of lung Ca OR >40 and haemoptysis unexplained

CXR offered for other symptoms

Question 7

What are features of Tumour Lysis Syndrome?

Answer 7

Life threatening complication- lysis of large amounts of cells

AKI
Cardiac Arrhythmia
Seizures
Hyperkalaemia
Hyperphosphataemia
Hypocalcaemia

Treat with IV rasburicase or IV allopurinol

Question 8

What is the management of meningitis?

Answer 8

> 3 months IV ceftriaxone
Age <3 months or >60 IV cefotaxime and amoxicillin

If travel outside UK within 3 months add vancomycin

Meningogococcal
- IV ceftriaxone