W05_09 Antibiotics Flashcards
ciprofloxacin kills what?
aerobic gram negative bacilli
levofloxacin, moxifloxacin, ofloxacin (resp fluoros) kill what?
aerobic gram negative bacilli
pneumonia bacteria;
aerobic gram positive cocci;
moxi- kills more anaerobes
macrolides in general kill which kinds of bacteria?
gram positive aerobic cocci
azithromycin kills what?
GP O2 cocci;
pneumonia;
some GN (diarrhea and gonorrhea)
metronidazole kills what?
c.diff!
anaerobes
clindamycin kills what?
anaerobes;
aerobic gram positive cocci (+MRSA -enterococci)
trimethoprin-sulphamethoxazole kills what?
broad spectrum, esp GN aerobic bacilli;
MRSA
vancomycin kills what?
GP O2 cocci (+enterococci +MRSA);
po vanco kills c. diff!
nitrofurantoin kills what?
GN O2 bacilli;
enterococcus
treatment for group A strep?
penicillin, amoxicillin;
first gen cephalosporins, macrolides, resp. fluoroquinolones
Rx for streptococcus pneumoniae?
penicillin or amoxicillin; 2/3rd gen cephs; macrolides; resp fluoros; doxycycline; vanco;
Rx for enterococcus fecalis?
amoxicillin;
vanco;
linezolid
Rx for staph aureus (methicillin sensitive)?
cloxacillin;
cephalosporin 1, vanco
Rx for MRSA in blood?
vanco;
linezolid
Rx for MRSA on skin or tissues?
clindamycin;
septra ds;
doxycycline
Rx for typical enteric pathogens?
cipro, cephs (3rd for GN O2 bacilli), amoxicillin-clavulanate;
aminoglycosides, pip-tazo, carbapenems;
septra or nitrofurantoin for cystitis
Rx for hemophilus influenzae?
amox-clav, ceph 2/3, resp fluor, clarithromycin, azithromycin
Rx for neisseria spp?
ceph 3 + azithromycin or doxy for gonorrhea (b/c chlamydia)
Rx for chlamydia trachomatis?
azithromycin or doxy
Rx for mycoplasma pneumoniae?
resp fluor (e.g. levofloxacin)
Rx for bacteroides spp.?
metronidazole (flagyl);
Rx for c.difficile?
metronidazole;
vanco
in general, penicillin used for?
strepto/pneumo cocci
in general, amox/ampi used for?
enterococci
in general, clox used for?
staph aureus
in general, ceph 1 used for?
staph aureus or group A strep (GP)
in general, ceph 2 used for?
H flu, pneumococcus
in general, ceph 3 used for?
pneumoccus, GN
in general, fluoroquinolones used for?
GN, resp tract
in general, macrolides used for?
group A strep, pneumococcus, staph aureus if penicillin allergy;
resp tract;
traveler’s diarrhea or chlamydia
in general, vanco used for?
GP (+MRSA, + enterococcus)
in general, aminoglycosides used for?
GN O2
in general, carbapenems or pip-tazo used for?
broad spectrum
in general, metronidazole used for?
anaerobes, esp gut
in general, clindamycin used for?
anaerobes above diaphragm, or GP
in general, septra or nitrofurantoin used for?
cystitis
in general, doxycycline used for?
chlamydia, resp tract
Pt has purulent tonsillitis. Cause? Rx?
Cause - group A strep likely.
Rx - penicillin, ceph 1, macrolide
Pt has cellulitis in leg. Cause? Rx?
Cause - group A strep or staph aureus likely.
Rx - ceph 1, cloxacillin
Pt has swollen knee and you suspect infection with negative gram staining. Cause? Rx?
Cause - staph aureus or gonorrhea.
Rx - clox or ceph 3 (+azithromycin)
Pt has acute otitis media. Cause? Rx?
Cause - strep pneumo, h.influenzae, moraxella catarrhalis.
Rx - amoxicillin, ceph 2/3, macrolides for resp tract
Pt has cystitis. Cause? Rx?
Cause - e.coli likely.
Rx - trimethoprim-sulfamethoxazole, nitrofurantoin
Pt has intra-abdominal sepsis. Cause? Rx?
Cause - GN O2 bacilli or AnO2.
Rx - ceph, aminoglycoside, cipro; or metronidazole (AnO2). meropenem or pip-tazo accounts for both.
Pt has meningitis. Cause? Rx?
s.pneumoniae (ceftriaxone, vanco),
h.influenzae (ceftriaxone),
meningococcus (ceftriaxone),
listeria (ampicillin
Pt has pneumonia. Cause? Rx?
Cause - s.pneumo, h.influ, m.pneuno, chlamydophila pneumo, legionella.
Rx - macrolide + beta lactam or doxycycline or resp fluor.
Pt travelling from latin america has watery diarrhea and fever. Cause? Rx?
Cause - GN O2s: salmonella, shigella, campylobacter, yersinia, e.coli.
Rx - fluoro or azithromycin