Valium

Question 1

Generic name

Answer 1

Diazepam

Question 2

Class

Answer 2

Benzodiazepine, anticonvulsant, sedative

Question 3

Mechanism of action

Answer 3

Acts on the Limbic system, the thalamus, and the hypothalamus to produce the sedative effects. Increases the seizure threshold; transient analgesia

Question 4

Indications

Answer 4

Anxiety, seizure activity, combative patient

Question 5

Contraindications

Answer 5

Allergy, myasthenia gravis

Question 6

Precautions

Answer 6

First trimester of pregnancy, watch for extravasation

Question 7

Adverse effects

Answer 7

Hypotension (rare) from rapid administration or from too high a dose. Brady cardia, respiratory arrest

Question 8

Incompatibilities/drug interactions

Answer 8

Don not mix or dilute with other solutions or drugs in syringe, tubing, or container

Question 9

Routs of Admin

Answer 9

IM/IV/IO

Question 10

Onset of action

Answer 10

Onset within minutes, peak effects variable and duration 20-50min

Question 11

Adult dose

Answer 11

0.1 mg/kg slow IVP (IM if unable to obtain IV)

Question 12

Pediatric dose

Answer 12

0.1 mg/kg slow IVP

Question 13

Special considerations

Answer 13

May prolong CNS depression in the neonate

IV doses may cause respiratory difficulties

Question 14

Protocols used

Answer 14

A-27: Seizures
B-12: Pediatric Seizures
E-19: Sedation and pain