Ativan

Question 1

Generic name

Answer 1

Lorasepam

Question 2

Class

Answer 2

Bensodiasepine, Anti-anxiety, Anti-convulsant

Question 3

Mechanism of action

Answer 3

Interacts with GABA receptor complex

Question 4

Indications

Answer 4

Anxiety, seizure activity

Question 5

Contraindications

Answer 5

Known hypersensitivity to benzodiazepines. Severe respiratory insufficiency unless being mechanically ventilated. Hepatic and/or Renal failure

Question 6

Precautions

Answer 6

Use caution with administration of other CNS depressants i.e. ETOH, narcotics, barbiturates, MAO, inhibitors and other antidepressants.

Question 7

Adverse Effects

Answer 7

Respiratory depression, hypotension, paradoxical reaction

Question 8

Adult dose

Answer 8

0.02-0.1 mg/kg, IVP

Question 9

Pediatric dose

Answer 9

0.02-0.1 mg/kg, IVP

Question 10

Special considerations

Answer 10

Resuscitative equipment for respiration support should be readily available
Protect from sunlight
Store in refrigerator

Question 11

Protocols used

Answer 11

A-19 Pre-eclampsia
A-22 Overdose
A-25 Psychiatric Emergencies
A-27 Seizures
B-10 Pediatric Seizures
E-17 Rapid Sequence Induction
E-19 Sedation
E-23 Field Prisoner Protocol