Atropine

Question 1

Trade name

Answer 1

Atropine

Question 2

Class

Answer 2

Parasympatholytic, anti-cholinergic

Question 3

Mechanism of Action

Answer 3

Clocks acetylcholine at parasympathetic neuroeffector sites, increases cardiac output, heart rate by blocking vagal stimulation in the heart; dies secretions by blocking cages nerve

Question 4

Indications

Answer 4

Symptomatic bradycardia, cholinergic crisis/ organophosphate poisoning

Question 5

Contraindications

Answer 5

Glaucoma, acute narrow angle glaucoma, second degree AVB type II and complete heart block (third degree AVB)

Question 6

Adverse Effets

Answer 6

Tachydysrhythmias, ventricular irritability, exacerbation/ initiation of angina

Question 7

Incompatibilities/ Drug interactions

Answer 7

sodium Bicarb

Question 8

Routs of Administration

Answer 8

Fast IV/IO

Question 9

Onset of Action

Answer 9

Onset immediate, Peak 1-2 minutes, duration 2-6 hrs

Question 10

Adult dose

Answer 10

0.5 mg IV/IO every 3-5 minutes as needed to max of 3mg

Question 11

Pediatric dose

Answer 11

0.02 mg/kg IV/IO minimum 0.1 mg: max single dose 0.5mg

Question 12

Special considerations

Answer 12

Pregnancy Category C

Antihistamines, phenothiazines, and tricyclic anti depressants can enhance effect of Atropine

Question 13

Protocols used

Answer 13

A-9 Bradyarrhythmias
A22a Overdose
B-5 Pediatric Brady Arrhythmias
E-19 Rapid sequence induction
E-24 weapons of mass destruction