Adenosine

Question 1

Class

Answer 1

Anti-dysrhythic, endogenous nucleoside

Question 2

Mechanism of action

Answer 2

Slows conduction time through the AV node; can interrupt the reentry pathways of the AV node. Onset of action within 5 to 20 seconds following an IV dose;half-life is 10 seconds

Question 3

Indications

Answer 3

To slow the rate of narrow complex tachycardia. He’s only effective on SVT and PSVT

Question 4

Contraindications

Answer 4

Sick sinus syndrome, Second and 3rd° AV block, known atrial fib relation\flutter, WPW

Question 5

Precautions

Answer 5

Has no effect on ventricular contractility, causes peripheral vasodilation

Question 6

Adverse effects

Answer 6

Transient dysrhythmias (sisterly, bradycardia, PVCs), bronchospasm, facial flushing, metallic taste

Question 7

Adult dose

Answer 7

Initial dose: 6 mg rapid IVP over 1–3 seconds followed by rapid 10 ml NS flush

Second dose: if no response within two minutes from initial dose 12 mg; rapid IVP with 10 mL NS flush.

Third dose: if no response within two minutes from second dose. 18 mg; rapid IVP with 10 mL NS flush.

Question 8

Pediatric dose

Answer 8

Initial dose: 0.1 mg/kg rapid IVP/IO Over 1-3 seconds. Maximum initial dose 6 mg

Second: if no response within two minutes from initial dose 0.2 mg/kg rapid IVP/IO maximum second dose not to exceed 12 mg

Question 9

Protocols used

Answer 9

A 12: PSVT

Be 9: pediatric PSVT

Question 10

Trade name

Answer 10

Adenocard