Cardizem

Question 1

Trade Name

Answer 1

Diltiazem

Question 2

Class

Answer 2

Calcium Channel blocker; Calcium antagonist

Question 3

Mechanism of Action

Answer 3

Inhibits Calcium ion influx across cell membranes during cardiac depolarization, decreases SA and AV conduction and dilates coronary and peripheral arteries and arterioles thereby slowing the rapid ventricular rate associated with atrial fibrillation and atrial fluter, and reduces coronary and peripheral vascular resistance

Question 4

Indications

Answer 4

Rapid ventricular response associated with atrial fibrillation / atrial flutter, SVT refractory to Adenosine

Question 5

Contraindications

Answer 5

Hypotension

Question 6

Adverse Effects

Answer 6

Hypotension, bradycardia, heart block, chest pain, systole, nausea and vomiting

Question 7

Incompatabilites/ Drug interactions

Answer 7

Poison induced or drug induces tachycardias

Question 8

Routes of admin

Answer 8

Slow IV IO bolus over 3-5 minutes followed by maintenance infusion drip

Question 9

Onset of action

Answer 9

onset is immediate, peak

Question 10

Adult dose

Answer 10

20mg IV over 2-3 minutes. may repeat 25mg in 15 minutes

Question 11

Pediatric dose

Answer 11

N/A

Question 12

Special Considerations

Answer 12

Monitor BP and HR Closely

Question 13

Protocols used

Answer 13

A-12 PSVT