Urinary System III Flashcards
The rate of urine formation is determined by the
Net pressure across glomerulus
How can you calculate the net pressure across glomerulus?
Outward pressure - inward pressure
Filtration happens only in the
Renal corpuscle
Reabsorption is the process by which
Solutes (glucose, ions, AA) and water get moved out, making way back into capillaries
The amount of reabsorption depends on
The endocrine system
What are the two pathways of Reabsorption?
- Transcellular
- Paracellular
The Transcellular pathway is one in which
Water and solutes move across the membrane of the cell, making their way through and being transported out into the interstitial space
The components of the Transcellular pathway make their way into the
Peritubular capillary
The Paracellular pathway is one in which
Water or solutes leak out in between cells (due to leaky tight junctions)
Reabsorption moves material from the
Lumen into the capillaries
Most of the reabsorption happens in the
Proximal convoluted tubule
The end of the nephron loops always have
Aquaporins
Filtrate moves from the proximal loop to the
Nephron Loop
The Descending loop of the Nephron is
Permeable to water but not solutes
The Descending loop has
Aquaporins across its length
The solute gradient found in the medulla of the kidney allows for water to
Leave by osmosis out of tubule
As filtrate moves down the descending limb, water moves
Out of the tubule via osmosis
As the filtrate moves down into the medulla, what happens?
More water will leave tubule
More water will leave tubule due to
The interstitial fluid getting saltier and saltier
The Ascending loop of the Nephron is
Not permeable to water but is permeable to solutes
What kind of transport is found in the Ascending loop?
Passive + Active transport of sodium and chloride
What moves stuff out of the lumen and into the interstitial space in the Ascending loop?
Sodium Pot pumps
What drives the concentration gradient in the medulla?
The Sodium Pot pumps
What happens as you move down medulla?
The solute concentration increases