The Immune System Flashcards

1
Q

What are the two categories of Innate Defenses?

A
  • Surface Barriers

- Internal Defenses

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2
Q

What are the two types of Surface Barriers?

A
  • Skin

- Mucus Membrane

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3
Q

What are the three types of Internal Defenses?

A
  • Cells
  • Chemicals
  • Physiological Responses
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4
Q

What are the two categories of Adaptive Defenses?

A
  • Humoral Immunity

- Cellular Immunity

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5
Q

Humoral Immunity consists of

A

B cells

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6
Q

Cellular Immunity consists of

A

T cells

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7
Q

The first line of defense is the

A

Innate System

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8
Q

What kind of barriers does the skin form?

A
  • Physical
  • Chemical
  • Biological
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9
Q

How does skin form a physical barrier?

A

Its stratified squamous epithelium creates a physical barrier

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10
Q

How does skin form a chemical barrier?

A

It has secretions of sweat and sebaceous glands

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11
Q

How does skin form a biological barrier?

A

It has dendritic cells and microflora

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12
Q

The respiratory system has modifications to

A

Stop pathogens

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13
Q

What are the modifications of the respiratory system?

A
  • Mucus-coated hairs in nose
  • Cilia of upper respiratory tract
  • coughing/sneezing
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14
Q

What are the nonspecific cells of the adaptive immune system?

A
  • Phagocytes
  • Natural Killer Cells
  • Eosinophils
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15
Q

What are Phagocytes?

A

WBCs that ingest and digest foreign invaders

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16
Q

What are examples of Phagocytes?

A
  • Neutrophils
  • Macrophages
  • Dendritic cells
17
Q

What are Natural Killer Cells?

A

Non-phagocytic lymphocytes that patrol blood and lymph

18
Q

What is the function of Natural Killer Cells?

A

They eliminate virus and bacteria-infected cells, along with tumor cells

19
Q

Natural Killer Cells initiate apoptosis, how?

A

They release cytotoxic chemicals like perforin and granzymes

20
Q

Eosinophils are nonspecific cells that respond to

A

Parasitic infections

21
Q

Antimicrobial proteins / chemicals are innate defenses which

A

Attack microorganisms directly or hinder their ability to reproduce

22
Q

What are two types of antimicrobial proteins?

A
  • Interferons

- Complement proteins

23
Q

Inflammation is an innate physiological response in which there is

A

Redness, heat, swelling, pain

24
Q

During tissue injury, what are released?

A

Chemical signals (like histamine)

25
What happens when there is tissue injury?
Dilation and increased leakiness are in the blood vessels and phagocytes migrate to the area
26
The tissue heals around the same time
Phagocytes consume bacteria and cell debris
27
During a fever, the leukocytes and macrophages exposed will secrete
Pyrogens
28
Pyrogen's interact with the body's
Hypothalamus, raising body temperature
29
What are the two forms of Humoral Immunity?
- Active | - Passive
30
What is naturally acquired Active Humoral Immunity?
Immunity is gained due to contact with either an infection or with a pathogen
31
What is artifically acquired Active Humoral Immunity?
Immunity is gained due to a vaccine
32
What is naturally acquired Passive Humoral Immunity?
Antibodies passed from mother to baby either via placenta or breastfeeding
33
What is artificially acquired Passive Humoral Immunity?
Babies receive an injection of antibodies (not vaccine)
34
T–lymphocytes act against
Target Cells
35
How do T-cells directly attack target cells?
They kill these infected cells
36
How do T-cells indirectly attack target cells?
- They release chemicals which enhance inflammatory response | - They activate other lymphocytes or macrophages