02/05 Flashcards

1
Q

1% of cardiomyocytes are

A

Pacemaker cells

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2
Q

Describe pacemakers

A
  • Can spontaneously depolarize

- No resting membrane potential

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3
Q

What is the pacemaker of the heart?

A

The SA node

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4
Q

The SA node depolarizes at

A

80 to 100 beats per minute

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5
Q

The Av node depolarizes at

A

40 to 60 beats per minute

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6
Q

Purkinje fibers depolarize at

A

20 to 40 beats per minute

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7
Q

The cells of the atria are connected via

A

Gap junctions

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8
Q

What are the three phases of AP in cardiomyocytes?

A
  • Depolarization
  • Plateau Phase
  • Repolarization
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9
Q

Why does skeletal muscle experience tetany?

A

It has a short refractory period

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10
Q

How is the refractory period in cardiac muscles?

A

Long

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11
Q

The heart rate is set by

A

The rate of depolarization / AP generation

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12
Q

What is displayed by an EKG / ECG?

A

Waves show what is happening in the heart with respect to depolarization and repolarization

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13
Q

What is the P wave?

A

The first wave that shows first electrical activity and is associated with atrial depolarization

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14
Q

What is the QRS complex wave?

A

Wave associated with ventricular depolarization and atrial repolarization

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15
Q

What is the T wave?

A

Wave that shows ventricular repolarization

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16
Q

What does the P-R interval say?

A

How long it takes for AP to get transmitted through whole conduction system

17
Q

Systole means

A

Contraction

18
Q

Diastole means

A

Relaxation

19
Q

80% of the blood in the ventricles is filled

A

Passively

20
Q

What happens during Isovolumetric contraction?

A

Both AV and SL valves are closed

21
Q

Isovolumetric contraction happens when

A

Ventricles contract

22
Q

What happens during Ventricular Dejection?

A

Pressure in ventricles is enough to open SL valves and blood is ejected out of the ventricles

23
Q

When ventricles relax there is

A

Isovolumetric relaxation

24
Q

What happens during isovolumetric relaxation?

A

All valves are closed and there is atrial relaxation