Digestive System II Flashcards
What is the function of the secreted HCl by the Parietal Cells?
Denatures proteins, activates pepsin, breaks plant cell walls and kills bacteria
What are the secreted Intrinsic Factors by the Parietal Cells?
Glycoproteins required for absorption of Vitamin B12 in small intestine
Chief Cells produce
Pepsinogen (inactive pepsin) and lipases
Pepsinogen is activated by
- HCl
- Pepsin
What is the function of the Lipases in the stomach?
They digest 15% of lipids
What do the Enteroendocrine Cells of the Mucosa layer do?
Release hormones
Gastrin is a hormone released by the stomach that
Causes increase in gastric secretions and increases motility / extent to which stomach muscles contract
What protects the stomach from its own stomach acid?
- Thick layer of bicarbonate-rich mucus
- Mucosal barrier
- Tight junctions between epithelial cells
The lining of stomach replaces itself every
3-6 days
Ulcers in stomach and duodenum are caused by
H Pylori
How does H Pylori cause ulcers?
Bacteria damages epithelial cells, decreasing production of mucus and increasing likelihood of ulcers
Gastric Emptying is when the stomach
Undergoes peristalsis
What happens during Gastric Emptying?
Chyme is pushed towards pyloric valve and then into the duodenum
Alcohol can get absorbed via
Stomach
Most nutrients are absorbed in the
Small Intestine
Most of the chemical digestion occurs in the
Small Intestine
What are the Accessory Organs of the Lower Intestinal Tract?
Pancreas, Liver, Gallbladder
What is the function of the Liver?
It produces Bile
What is the function of the Bile?
It emulsifies lipids
Bile travels to the duodenum via
Hepatic ducts
Bile gets stored in
Gallbladder
The Pancreas has both an endocrine and exocrine function. Describe both:
- Endocrine: Produce insulin and glucagon
- Exocrine: Produces digestive enzymes
What is the function of insulin and glucagon?
They handle blood sugar levels
What is the function of the Gallbladder?
It stores and concentrates bile
Compared to the stomach, the small intestine tract lacks
Modifications to protect itself from acidic environment
The Duodenum is the uppermost region of the Small Intestine and is where
Chyme gets mixed with the secretions of liver (bile), gallbladder, and pancreas (pancreatic juice)
The Jejunum is the second region of the Small Intestine and is where
Most of chemical digestion and absorption takes place
The Ileum is the region of the Small Intestine that
Connects to the Large Intestine
What increases the Surface Area in the Small Intestine?
- Circular Folds
- Villi
- Motility
What is the function of the SI’s Circular Folds?
- Slows down how quickly food moves through the small intestine
- Insures that as chyme moves down, it spirals around and comes in contact with the lining
The Villi of the Small Intestine are
Fingerlike projections that come off circular folds
Each Villi contains
- Epithelial cells, which produce Mucus
- Networks of capillaries
- Lacteals, which absorb lipids and lipid-soluble vitamins
- Microvilli