Urinary System Flashcards

1
Q

What organ creates urine?

A

Kidney

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2
Q

T/F: if you’re dehydrated enough, your kidneys won’t produce urine

A

FALSE: obligate urine production

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3
Q

What are other functions of the kidney aside from urine production?

A

Control blood volume/BP, pH, hormone production, vit D metabolization (Ca++ reuptake)

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4
Q

What hormones are produced in the kidneys?

A

Renin (BP regulator), Erythropoietin

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5
Q

Describe the position of the kidneys in the thorax

A

Retro-peritoneal; posterior to the peritoneal cavity

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6
Q

What protects the kidneys?

A

Relatively little compared to the rest of the thoracic organs; surrounded by fat to provide shock absorption

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7
Q

What is the functional unit of the kidney?

A

Nephron

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8
Q

What is the glomerulus?

A

Specialized (fenestrated) capillary bed at the beginning of a nephron; site of filtration of blood

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9
Q

What is the renal tubule?

A

Location in a nephron where blood filtrate becomes urine

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10
Q

Describe blood flow through the kidney

A

Enters through renal artery, afferent arteriole->glomerular capillaries, exits glom cap thru efferent arteriole->peritubular capillaries to venule to renal vein… PORTAL SYSTEM

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11
Q

What are the steps in urine formation?

A

1: Glomerular filtration
2: Tubular Reabsorption
3: Tubular Secretion

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12
Q

What is glomerular filtration?

A

Filtration of liquid out of the glomerular capillary and into the renal tubules of the kidney

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13
Q

What structure captures glomerular filtrate BEFORE entering the renal tubule?

A

Bowman’s capsule

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14
Q

What pressures affect GFR (glomerular filtration rate)?

A

Glomerular hydrostatic pressure (pressure pushing fluid out, glom.->capsule); colloid osmotic pressure (plasma proteins, pull fluid back in); bowman’s capsule hydrostatic pressure (pushing fluid back in, capsule->glom.)

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15
Q

What happens to glomerular hydrostatic pressure when the afferent arteriole constricts?

A

Decreases; less blood flow into the glomerulus means less pressure

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16
Q

Describe the interactions of pressures around the glomerulus

A

Opposing pressures; GHP wants to push fluid out of the capillary, COP wants to pull fluid back into the capillary, BCHP wants to push fluid back to the capillary

17
Q

What are the cells of the bowman’s capsule?

A

Podocytes; wrap around glomerular capillary, filtrate can escape capillary through filtration slits (space between podocyte arms)

18
Q

What can escape the capillary through fenestrations and filtration slits?

A

Everything in the plasma EXCEPT blood cells and proteins (restricted by basal lamina/basement membrane)

19
Q

What unit is responsible for urine formation?

A

Nephron; about 1 million of them in each kidney!

20
Q

How much urine is filtered daily?

A

About 200L of blood -> 1-1.5L urine/day