Female reproductive physiology Flashcards
What cells bind GnRH?
glandular cells of the anterior pituitary
What cells bind FSH and LH?
Follicle cells of the ovaries
What cells bind estrogen?
Many throughout the body–uterine lining, mammary glands, brain, muscle, bone, etc
What cells secrete estrogen and progesterone?
Follicle cells
What hormones primarily influence the ovarian cycle?
FSH, LH
What happens to follicle cells left in the ovary after ovulation?
LH causes growth of the corpus luteum
What hormones primarily influence the uterine cycle?
estrogen and progesterone
What is the proliferative phase?
phase of the uterine cycle characterized by thickening of the emdometrium
What is the secretory phase?
phase of the uterine cycle characterized by production of sugary secretions from the endometrium
What triggers menses?
Death of the corpus luteum leading to a drop in estrogen and progesterone
How do follicles grow in size/mature?
Mitosis of follicle cells
What does inhibin do?
Creates negative feedback loop; secreted by follicle cells, it binds to the ant. pit. and hypothalamus to inhibit GnRH, FSH, LH
What triggers ovulation?
Spike in LH caused by the negative feedback; growing levels of est. and inh. cause drop in GnRH and FSH, large spike in LH
What is the dominant hormone produced by the corpus luteum?
Progesterone
What effect does progesterone have on the uterine cycle?
Stimulates endometrial glands–secretory phase