Unit 1 - Gorden Mastitis Lecture

Question 1

Order the following from most common to least common result of a culture for mild clinical mastitis:
Gram negative, Staphylococcus, Other, Streptococcus, and No growth

Answer 1

No growth > Gram negative > Streptococcus > Staphylococcus > Other

Question 2

In cases of mild mastitis, how long should therapy last?

Answer 2

4-5 days post resolution of clinical signs

Question 3

In cases of severe mastitis, how long can/should therapy last?

Answer 3

It could potentially never end

Question 4

What are the top three intra-mammary products used for mastitis treatment?

Answer 4

Spectramast LC, Pirsue, and Cefa-Lak

Question 5

Which of the top three intra-mammary products for mastitis treatment has no gram negative activity?

Answer 5

Pirsue

Question 6

What is the best route of administration for beta-lactams in the treatment of mastitis?

Answer 6

Intra-mammary

Question 7

True or False: If you increase milking from 2x to 3x per day the elimination of the drug will be unaffected

Answer 7

False

Question 8

Which of the top 3 intra-mammary mastitis treatments have been OK’d for 3x a day treating?

Answer 8

Pirsue and Spectramast LC but you have to dose 2x a day

Question 9

Should your intra-mammary antibiotic go entirely into the teat canula or partially into the teat canula? Why?

Answer 9

partially - If you put it entirely into the teat canula you can push bacteria into the teat cistern making the infection worse

Question 10

If you chose to use gentocin for mastitis treatment, what is the recommended slaughter withdrawal time?

Answer 10

30 months

Question 11

What systemic drugs (general) are best for systemic therapy of mastitis?

Answer 11

Drugs that are weak basic, not highly bound, and are lipid soluble

Question 12

What systemic drugs (specifically) are best for systemic therapy of mastitis?

Answer 12

Macrolides, trimethoprim, tetracyclines, and fluoroquinolones

Question 13

Is it legal to use fluoroquinolones for treatment of mastitis in cows?

Answer 13

NO! It would work well, but it is not legal

Question 14

Mastitis milk has a higher or lower pH than normal?

Answer 14

higher

Question 15

What are the three compartments that need to be treated in cows with mastitis?

Answer 15

Milk and ducts, parenchyma, and the cow

Question 16

What are most severe clinical mastitis cases due to?

Answer 16

Coliform mastitis - it often results in bacteremia

Question 17

What supportive care is recommended for severe clinical mastitis patients?

Answer 17

Hypertonic or isotonic fluid
NSAIDs
Steroids
Calcium
Assess/Fix the acid base status

Question 18

What is the theory to treating sub-clinical mastitis (even though treatment hasn’t resulted in this goal)?

Answer 18

Reduce incidence of chronic subclinical infections should result in improved SCC and milk production

Question 19

Dry cow therapy is effective in doing what?

Answer 19

Clearing infections during the first 10-14 days of the dry period

Question 20

Are mastitis infections in small ruminants more commonly due to gram positive or gram negative organisms?

Answer 20

gram positive organisms