ToRCHeS infections

Question 1

Toxoplasma gondii

Answer 1

Cat feces or ingestion of undercooked meat

Materal: asymptomatic

Neonatal: chorioretinitis, hydrocephalus, intracranial calcifications

Question 2

Rubella

Answer 2

Respiratory droplets

Maternal: Rash, lymphadenopathy, arthritis

Neonatal: PDA, cataracts, deafness, blueberry muffin rash

Question 3

CMV

Answer 3

Sexual contact, organ transplants

Maternal: Asymptomatic, mononucleosis-like

neonate: hearing loss, seizures, petechial rash, blueberry muffin rash

Question 4

HIV

Answer 4

Sexual contact, needlestick

Maternal: Variable

Neonate: recurrent infections, chronic diarrhea

Question 5

HSV-2

Answer 5

Skin or mucous membrane contact

Maternal: usually asymptomatic, herpetic lesions

Neonate: encephalitis, herpetic lesions

Question 6

Syphilis

Answer 6

Sexual contact

Neonate: stillbirth, hydrops fetalis; if survives, facial abnormalities (notched teeth, saddle nose, short maxilla), saber shins, CN VIII deafness