Blood transfusion reactions Flashcards
1
Q
Allergic reaction
A
Type I hypersensitivity against plasma proteins in transfused blood
Urticaria, pruritis, wheezing, fever. Treat with antihistamines
2
Q
Anaphylactic reaction
A
Severe reaction IgA deficient individuals must receive blood products that lack IgA
Dyspnea, bronchospasm, hypotension, respiratory arrest, shock
3
Q
Febrile nonhemolytic transfusion reaction (FNHTR)
A
Type II hypersensitivity reaction. Host antibodies against donor HLA antigens and leukocytes
Fever, headaches, chills, flushing
4
Q
Acute hemolytic transfusion reaction (HTR)
A
Type II hypersensitivity reaction. Intravascular hemolysis (ABO blood group incompatibility) or extravascular hemolysis (host antibody reaction against foreign antigen on donor RBCs)
