Chromosomal translocations Flashcards
1
Q
t(9;22) (Philadelphia chromosome)
A
CML (bcr-abl hybrid)
Philadelphia CreaML cheese.
2
Q
t(8;14)
A
Burkitt’s lymphoma (c-myc activation)
3
Q
t(11;14)
A
Mantle cell lymphoma (cyclin D1 activation)
4
Q
t(14;18)
A
Follicular lymphomas (bcl-2 activation)
5
Q
t(15;17)
A
M3 type of AML (responsive to all-trans retinoic acid)