G-protein linked 2nd messengers

Question 1

alpha1

Answer 1

q

sympathetic

increases vascular smooth muscle contraction, increases pupillary dilator muscle contraction (mydriasis), increases intestinal and bladder sphincter muscle contraction

Question 2

alpha2

Answer 2

i

sympathetic

decreases sympathetic outflow, decreases insulin release, decreases lipolysis, increases platelet aggregation

Question 3

beta1

Answer 3

s

sympathetic

increases heart rate, increases contractility, increases renin release, increases lipolysis

Question 4

beta2

Answer 4

s

sympathetic

vasodilation, bronchodilation, increases heart rate, increases contractility, increases lipolysis, increases insulin release, decreases uterine tone (tocolysis), ciliary muscle relaxation, increases aqueous humor production

Question 5

M1

Answer 5

q

parasympathetic

CNS, enteric nervous system

Question 6

M2

Answer 6

i

parasympathetic

decreases heart rate and contractility of atria

Question 7

M3

Answer 7

q

parasympathetic

increases exocrine gland secretions, increases gut peristalsis, increases bladder contraction, bronchoconstriction, increases pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accomodation)

Question 8

D1

Answer 8

s

relaxes renal vascular smooth muscle

Question 9

D2

Answer 9

i

modulates transmitter release, especially in brain

Question 10

H1

Answer 10

q

increases nasal and bronchial mucus production, contraction of bronchioles, pruritus and pain

Question 11

H2

Answer 11

s

increases gastric acid secretion

Question 12

V1

Answer 12

q

increases vascular smooth muscle contraction

Question 13

V2

Answer 13

s

increases H2O permeability and reabsorption in the collecting tubules of the kidney