Malignant Breast Tumors Flashcards

1
Q

ductal cell carcinoma in situ (DCIS)

A

Noninvasive

Fills ductal lumen. Arises from dual hyperplasia

Early malignancy without basement membrane penetration

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2
Q

comedocarcinoma

A

Noninvasive

ductal, caseous necrosis. Subtype of DCIS

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3
Q

Invasive ductal

A

Invasive

Firm, fibrous, rock-hard mass with sharp margins and small, glandular, duct-like cells. Classic stellate morphology

worst and most invasive; most common (76% of all breast cancers)

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4
Q

Invasive lobular

A

Invasive

Orderly row of cells (indian file)

often bilateral with multiple lesions in the same location

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5
Q

Medullary

A

Invasive

Flashy, cellular, lymphocytic infiltrate

good prognosis

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6
Q

Inflammatory

A

Invasive

Dermal lymphatic invasion by breast carcinoma. Peau d’orange (breast skin resembles orange peel); neoplastic cells block lymphatic drainage

50% survival at 5 years

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7
Q

Paget’s disease

A

Invasive

Eczematous patches on nipple. Paget cells = large cells in epidermis with clear halo

Suggests underlying DCIS. Also seen on vulva

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