Ovarian non-germ cell tumors

Question 1

Serous cystadenoma

Answer 1

45% of ovarian tumors. Frequently bilateral, lined with fallopian tube-like epithelium. Benign

Question 2

Serous cystadenocarcinoma

Answer 2

45% of ovarian tumors, malignant and frequently bilateral. Psammoma bodies seen on histology

Question 3

Mucinous cystadenoma

Answer 3

Multilocular cyst lined by mucus-secreting epithelium. Benign. Intestine-like tissue

Question 4

Mucinous cystadenocarcinoma

Answer 4

Malignant. Pseudomyxoma peritonei–intraperitoneal accumulation of mutinous material from ovarian or appendices tumor

Question 5

Brenner tumor

Answer 5

Benign and unilateral. Looks like bladder. Solid tumor that is pale yellow-tan in color and appears encapsulated. Coffee ban nuclei on H and E staining

Question 6

Fibromas

Answer 6

Bundles of spindle-shaped fibroblasts. Meigs’ syndrome–triad of ovarian fibroma, ascites, and hydrothorax. Pulling sensation in groin

Question 7

Granulosa cell tumor

Answer 7

secretes estrogen–> precocious puberty (kids). Can cause endometrial hyperplasia or carcinoma in adults. Cell-Exner bodies–small follicles filled with eosinophilic secretions. Abnormal uterine bleeding

Question 8

Krukenberg tumor

Answer 8

GI malignancy that metastasizes to ovaries, causing a mucin-secreting signet cell adenocarcinoma