Sympathetic and Parasympathetic A.N.S Flashcards
Enzyme of Sympathetic Nervous system:
Norepinephrine NE
Enzymes that DESTROY norepinephrine (HYDROLYSIS):
- Mono-Amine Oxidase MAO
- Catechol-O-Methyl Transferase COMT
how does MAO and COMT destroy NE:
by HYDROLYSIS
Receptors of Sympathetic NS:
Alpha 1
Alpha 2
Beta 1
Beta 2
Beta 3
Degraded Product of NE:
Vanillyl-Mandelic acid
effector organs of ALPHA-1 receptors:
Conjunctival Vessels
Dilator Pupillae
Trabecular Meshwork
Mueller’s Muscle
Alpha-1 effect on Conjunctival Vessels:
Vasoconstriction
Alpha-1 effect on Dilator Pupillae:
Mydriasis (contract)
Alpha-1 effect on Trabecular Meshwork:
Open DIRECTLY - LOWER IOP
Alpha-1 effect on Mueller’s muscle:
Lid RETRACTION
Alpha-2 effector organ:
Ciliary Process - INHIBITORY
Alpha-2 effect on Ciliary Process (inhibitory):
Decrease AH secretion
BETA-1 effector organs:
Heart
GIT
BETA-1 effect on Heart:
Increase Heart Rate
Increase BP
Tachycardia
BETA-1 effect on GIT:
Relax