Fundamentals of Pharmacology Flashcards

1
Q

science which deals with all knowledge about drugs

A

Pharmacology

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2
Q

– action of the body in the drugs once it is introduced into the BODY

A

Pharmacokinetics

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3
Q

how the body handle the drugs

A

Pharmacokinetics

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4
Q
  • “what the body does to the drugs”
A

Pharmacokinetics

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5
Q

movement of drug molecules from the site of administration (routes) to the systemic blood circulation

A

Absorption / Bioavailability

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6
Q

movement of drug molecules to the different parts of the body until some of the drugs reach the site of action

A

Distribution

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7
Q

– transformation/change of drug molecules from bound form (inactive) to free/unbound form active or reverse or leads to formation other forms of drug, active or inactive, called inactive metabolites (usually inactive → no effect)

A

Metabolism / Biotransformation

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8
Q

Organs involved in Drug metabolism

A
  • Liver
  • Kidneys
  • Lungs
  • Adrenal or Suprarenal glands
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9
Q

movement of drug molecules out of the body → termination of drug effect (E)

A

Elimination / Excretion

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10
Q
  • disappearance of drug molecules from the blood/body → termination of drug effect (E)
A

Excretion/Elimination

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11
Q

Organs involved for drug excretion:

A
  • Kidneys
  • Liver
  • Glands
  • Lungs
  • Git
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12
Q

side effects of Tetracycline:

A

Yellow discoloration of Body secretions

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13
Q

action of drugs in the body

A

Pharmacodynamics

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14
Q
  • “what the drug does to the body
A

Pharmacodynamics

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15
Q

study of biochemical and physiological effects of drugs in the body or microorganisms and mechanism of drug action and the relationship between drug concentration and effects

A

Pharmacodynamics

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16
Q

how the drugs act in the body or foreign bodies (microbes/CA cells

A

Mechanism of Action

17
Q

desired effects in the body

A

pharmacologic Effects

18
Q

uses of the drugs for treatment of diagnosis

A

Indications

19
Q

conditions/factors to withhold the use of drugs → Harmful

A

Contra-Indications

20
Q

study of drug dosage:

A

Posology

21
Q

– deals with the studies on the effects of drugs upon the eye and its appendages

A

Ocular Pharmacology

22
Q

chemical substance, natural, semi-synthetic or synthetically acquired, when introduced into the body→ alter the normal body functions or inhibit or kill foreign bodies (effects)

A

Drugs / Medications

23
Q

Type of Effects of drugs:

A
  • Pharmacologic or Therapeutic Effects
  • Side or Untoward effects
  • Adverse or Toxic Effects
24
Q

expected clinical manifestations after taking therapeutic dose

A

Side effects / Untoward effects

25
Q

unexpected clinical manifestations after taking toxic or overdose of the drugs

A

Adverse or Toxic Effects

26
Q

study of adverse or toxic effects of the drugs

A

Toxicology

27
Q

Prescribers of Drugs (Doctors)

A
  1. MD
  2. Veterinarian MD
  3. DDM (Dentist)
  4. OD (DPA’s for detection of disease)
28
Q

test to confirm TB:

A

Chest X-ray

Sputum microscopy

Protein Purified Derivative (PPD - skin testing)

29
Q

Anti-TB agents (RIPE):

A
  • Rifampicin
  • Isoniazid
  • Pyrazinamide
  • Ethambutol
30
Q

concerned with the identification of crude effect of natural–occurring drugs

A

Pharmacognosy

31
Q

Contraindication of most of Medications:

A
  1. Pregnancy (1st trimester)
  2. Lactating mammary glands
32
Q

TB drugs that cause Peripheral Sensory Neuropathy (Neuritis) :

A

INH Isoniazid

Pyrazinamide

Ethambutol

33
Q

dosage of Isoniazid:

A

5mg per bodyweight - 5mg/kg

34
Q

Hepatotoxic TB drugs (drug induced hepatitis):

A
  • Isoniazid INH
  • Pyrazinamide
35
Q

TB medication that cause reddish discoloration of urine:

A

Rifampicin

36
Q

Vitamins that reverse Peripheral Sensory Neuropathy caused by TB meds:

A

Vitamin B complex

b1 - thiamine

b6 - pyridoxine

b12 - cyanocobalamin

37
Q

2 months TB medications:

A

R.I.P.E

+

VIT B COMPLEX

38
Q

4 months TB medications:

A

R.I.E

+

VIT B COMPLEX

39
Q

Ingredients of Ophthalmic solution:

A
  • Distilled water
  • Benzalkonium chloride (BAC)
  • Thimerosal (disinfectant)
  • EDTA
  • Methylcellulose
  • Boric acid/Na borate