pharma Terminologies

Question 1

lowest concentration of the drugs to produced the desired pharmacologic effects

Answer 1

Potency

Question 2

highest concentration of drug to produced the desired pharmacologic effects -

Answer 2

Efficacy

Question 3

• maximum effect of a drug regardless of the drug conc.

Answer 3

Effectiveness

Question 4

– finished dosage form of the drug containing active ingredients

Answer 4

Drug product

Question 5

– chemical components responsible for claimed therapeutic effects of the drug product

Answer 5

Active Ingredients

Question 6

meaning of EDTA

Answer 6

Ethylene - Di amine - Tetra - Acetate

Question 7

drug product whose patent has been expired or never been patented

Answer 7

Generic Drug

Question 8

shortened scientific name base on active ingredient, widely used

Answer 8

Generic name

Question 9

complete description of chemical structure of drug,

not used

Answer 9

Chemical name

Question 10

– name given by pharmaceutical company to distinguished their drug products from other competitors although it contains the same active ingredient(s)

Answer 10

Brand name

Trade name

Propriety Name

Question 11

most abused OTC drug

Answer 11

Paracetamol / Acetaminophen

Question 12

most abused prescription drug

Answer 12

Amoxicillin

Question 13

rate (time) of absorption

Answer 13

Bioavailability

Question 14

– time it takes for ½ of the drug to be eliminated

at constant rate of 0.693 t ½

Answer 14

Half-Life

Question 15

– art of treating the diseases

Answer 15

Therapeutics

Question 16

application of drugs for the treatment of the disease

Answer 16

Pharmacotherapeutics

Question 17

– deal with drugs w/c are capable of destroying microbes or foreign bodies w/o destroying/sparing host

Answer 17

Chemotherapy

Question 18

deals with procurement, preparation & dispensing of drugs

Answer 18

Pharmacy

Question 19

drug produces usual effect at unexpected low dosage

Answer 19

Hypersensitivity / Hyperreactive

Question 20

Drug produces usual effect at unexpected high dose

Answer 20

Hyposensitivity / Hyporeactive

Question 21

decrease sensitivity acquired as a result of prior exposure to the drug due to enzyme induction metabolizing more drugs thus decrease plasma effect

Answer 21

Tolerance

Question 22

tolerance rapidly develop after administration of only few drug doses

Answer 22

Tachyphylaxis

Question 23

– reduced sensitivity as a result of antibody formation

Answer 23

Immunity

Question 24

– increase sensitivity as a result of denervation (allergy)

Answer 24

Super sensitivity

Question 25

any other unwanted reactions to pharmaceutical administration that has no obvious logical pharmacodynamic cause and can not be attributed to hypersensitivity

Ex. Mydriatic that causes miosis

Answer 25

Idiosyncratic reactions

Question 26

drug toxicity in Elderly is caused by?

Answer 26

impaired liver function

slow down drug metabolism

Question 27

drug toxicity in children is caused by?

Answer 27

immature liver

increase risk of drug toxicity

Question 28

they are high risk of drug toxicity for unknown reason

Answer 28

Women

Question 29

substance w/o intrinsic pharmacologic activity but may yield valuable therapeutic effect

Answer 29

Placebo

Question 30

meaning of PPSR

Answer 30

Physio Psycho Somatic Reactions

Question 31

Appearance of differences in magnitude of response among individuals in the same population given the same dose of the drugs

Answer 31

Variance

Question 32

a dose-response influenced by:

• receptor & effector of response
• binding of drug to receptor

Answer 32

Slope of dose-effect curve