Cholinergic antagonist / parasympatholytics

Question 1

Cholinergic Antagonist / Parasympatholytic agents

Muscarinic Blockers:

Answer 1

Alkaloids - atropine, Scopolamine

Semi-synthetic - Homatropine, methscopolamine, eucatropine

Synthetic - Cyclopentolate, Tropicamide

Botulinum A toxin

Question 2

Nicotinic Blockers:

Answer 2

Ganglionic blockers

Neuromuscular blockers - curare

Question 3

uses of Atropine:

Answer 3

Penalization therapy

Cycloplegic refraction in children

Anterior Uveitis - break posterior synechiae

Question 4

used for treatment for Iridocyclitis:

Answer 4

Scopolamine 0.25%

Question 5

used for provocative test for suspected narrow angle/close angle glaucoma

Answer 5

Eucatropine

Question 6

drug of choice for routine cycloplegia:

Answer 6

Cyclopentolate 0.5% 1% 2%

Question 7

causes seizure, psychosis, hallucination, disorientation, drowsiness in children

Answer 7

2% Cyclopentolate

Question 8

Cyclopentolate dosage to prevent CNS side effects/ seizure:

Answer 8

0.5% - 1% Cyclopentolate

Question 9

most commonly used mydriatic & cycloplegic

weak cycloplegic

drug of choice for routine mydriasis

Answer 9

0.5% - 1% Tropicamide - MYDRIACYL

Question 10

IOP elevates using ____ tropicamide but not _____

Answer 10

1%

0.5%

Question 11

used for surgical treatment of Strabismus

Answer 11

Botulinum A toxin - BOTOX

Question 12

used for skeletal muscle paralysis

especially for intubation

Answer 12

Nicotinic blockers

Neuromuscular blockers - Curare

Question 13

reversing agent for Tropicamide:

Answer 13

2% Pilocarpine

or

0.5% Dapiprazole