Miotic & Mydriatic agents mixed

Question 1

Systemic S/E of Pilocarpine:

Answer 1

Salivation, lacrimation & sweating - stimulate glandular secretions

worsen Parkinson

Increase GIT motility - nausea, vomiting, diarrhea

Question 2

Indirect acting Parasympathomimetic agents:

Answer 2

Acetylcholinesterase Inhibitors

Carbamyl ester inhibitor

Organophosphorus Inhibitors

Question 3

a pharmacological test used for the diagnosis of certain neural disease, especially myasthenia gravis

Answer 3

Tensilon test or Edrophonium test

Question 4

diagnostic Agent for Myasthenia Gravis:

Answer 4

Edrophonium

Question 5

Drug of Choice for Myasthenia Gravis:

Answer 5

Neostigmine

Question 6

Antidote for Physostigmine poisoning (intense miosis):

Answer 6

• Atropine 2mg every 5 mins until symptoms reverse
• Pralidoxime

Question 7

AchEsterase inhibitors for Open angle glaucoma:

Answer 7

Physostigmine

Echothiophate

DFP

Demecarium

Question 8

Carbamyl ester inhibitors (reversible effect) :

Answer 8

Physostigmine

Demecarium

Neostigmine

Ambenonium

Pyridostigmine

Edrophonium

Question 9

Organophosphorus inhibitors (irreversible effect):

Answer 9

Echothiophate

DFP - Diisoprophyl Fluorophosphate

Parathion

Nerve Gas

Question 10

Uses of Physostigmine:

Answer 10

Open angle Glaucoma

Synechial Glaucoma

pediculosis (lice) of eyelid margins

Question 11

Major side effects of Physostigmine:

Answer 11

Accommodative spasm with induced Myopia

anterior sub-capsular cataract

Retinal detachment

Question 12

long acting miotic agent

causes retinal detachment

Answer 12

Echothiophate

Question 13

Use of Echothiophate:

Answer 13

Accommodative Esotropia

Question 14

long acting miosis (2-4 weeks)

Answer 14

DFP