Enhancement of drug effect

Question 1

2 drugs in combination:

Answer 1

Enhancement of Drug Effect

Question 2

occurs if 2 drugs with same effect when given together will produce an effect Equal in magnitude to the sum of effects when the drugs are given individually

Answer 2

Additive

Question 3

occurs if 2 drugs with the same effect, when given together will produce an effect Greater in magnitude to the sum of effects when the drugs are given individually

Answer 3

Synergism

Question 4

– occurs if 1st inactive drug lacking an effect of its own, increases the effect of the 2nd active drug but NO same effect

Answer 4

Potentiation

Question 5

Ampicillin + Amoxicillin → both broad spectrum penicillin

Answer 5

Additive

Question 6

Enhancement of drug effect when NSAID-ibuprofen is combined with paracetamol:

Answer 6

Synergism

Question 7

Enhancement of drug effect of combination of echothiopate with phenylephrine at the pupil

Answer 7

antagonism

Question 8

Enhancement of drug effect when vasopressor agent -adrenaline (Epinephrine) is incorporated with local anesthetic agent lidocaine:

Answer 8

potentiation

Question 9

Enhancement of drug effect of combination of atropine with physostigmine:

Answer 9

Antagonism

Question 10

Enhancement of drug effect of combination of pilocarpine with epinephrine at the pupil:

Answer 10

Antagonism

Question 11

Enhancement of drug effect if NSAID- Ibuprofen is combined with NSAID-mefenamic acid:

Answer 11

Additive