Substance P/Neurokinin 1 Receptor Antagonists Flashcards

1
Q

Medications

A
  • aprepitant

- rolapitant

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2
Q

Action

A

acts directly in CNS to block receptors associated with nausea and vomiting

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3
Q

Contraindication

A
  • allergy
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4
Q

Cautions

A
  • pregnancy

- lactation

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5
Q

Adverse Effects

A
  • anorexia
  • fatigue
  • constipation
  • diarrhea
  • liver enzyme elevation
  • dehydration
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6
Q

Drug-Drug Interactions

A
  • warfarin

- hormonal contraceptives

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