Substance P/Neurokinin 1 Receptor Antagonists Flashcards
1
Q
Medications
A
- aprepitant
- rolapitant
2
Q
Action
A
acts directly in CNS to block receptors associated with nausea and vomiting
3
Q
Contraindication
A
- allergy
4
Q
Cautions
A
- pregnancy
- lactation
5
Q
Adverse Effects
A
- anorexia
- fatigue
- constipation
- diarrhea
- liver enzyme elevation
- dehydration
6
Q
Drug-Drug Interactions
A
- warfarin
- hormonal contraceptives