Disease Modifying Antirheumatic Drugs (DMARDs) - General Flashcards
1
Q
Medications
A
COMMON TUMOR NECROSIS FACTOR (TNF) BLOCKERS
- Adalimumab
- Infliximab
- Etanercept
2
Q
Actions
A
- Act to decrease the local effects of TNF, a locally released cytokine that can cause the death of tumor cells and stimulate a wide range of proinflammatory activities
- Often the first class used with progressing arthritis
- Drug side effects can be severe or life-threatening
3
Q
Contraindications
A
-Can not be used in anyone with an acute infection, cancer, sepsis, tuberculosis, hepatitis, myelosuppression or demyelinating disorders
4
Q
Cautions
A
- Pregnancy/lactation
- Hepatic and renal dysfunction
5
Q
Adverse effects
A
-BLACK BOX WARNING: risk of serious fatal infections and the development of lymphomas and other cancers
6
Q
Drug-drug
A
-Immune suppressant drugs and live vaccines
7
Q
Assessment
A
- History: allergy, lesions, contraindications or cautions
- Physical: temp, VS, CNS status, cancer screening, monitor ROM and pain levels
8
Q
Nursing diagnoses
A
- Acute pain r/t CNS, disease process
- Risk for infection r/t drug effects
- Anxiety r/t disease process and drug effects
- Deficient knowledge
9
Q
Evaluation
A
- Monitor patient response
- Evaluate the effectiveness of the teaching plan
- Evaluate the effectiveness of comfort measures
- Evaluate patient compliance with the regimen
