Proton Pump Inhibitors Flashcards

1
Q

Medications

A

“-prazole”

  • omeprazole
  • esomeprazole
  • lansoprazole
  • pantoprazole
  • rabeprazole
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Action

A

Act at specific secretory surface receptors to prevent final step of acid production lowering stomach acid level

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Indications

A

Short-term treatment:

  • active duodenal ulcers
  • GERD
  • erosive esophagitis
  • benign active gastric disease

Long term:
- pathological hypersecretory conditions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Contraindications

A
  • allergy
  • pregnancy
  • lactation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Adverse Effects

A
  • dizziness - abdominal pain
  • headache - tongue atrophy
  • asthenia - cough
  • vertigo - stuffy nose
  • insomnia - hoarseness
  • apathy - epistaxis
  • diarrhea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drug-Drug Interactions

A

Clopidogrel = increased CV effects

Bensodiazepines, Phenytoin, Warfarin = increase risk of toxicity

Ketoconazole, theophylline = decreased levels

Sulcrafate = PPI’s not absorbed well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly