Angiotensin II Receptor Blockers Flashcards
1
Q
Medications
A
“-sartan”
- Candesartan
- Irbesartan
- Losartan
- Olmesartan
- Telmisartan
- Valsartan
2
Q
Action
A
- Angiotensin II receptor antagonist
- Blocks angiotensin II from binding with the receptors on vascular smooth muscle and in the adrenal cortex
- Prevents vasoconstriction and release of aldosterone
3
Q
Indications
A
- HTN
- CHF
- Diabetic nephropathy prevention
4
Q
Contraindications
A
- Allergy
- Pregnancy (BLACK BOX WARNING)
5
Q
Caution
A
- Hepatic dysfunction
- Renal dysfunction
- Hypovolemia
6
Q
Adverse effects
A
- CNS: HA, dizziness, syncope, weakness
- CV: Hypotension
- GI complaints
- Skin: Rash
- Hyperkalemia
- Renal damage
7
Q
Drug-Drug interactions
A
- NSAIDs
- Other drugs affecting the RAAS
8
Q
Assessment
A
- Liver impairment
- Labs: Liver fx
9
Q
Implementation
A
- Can take with or without food
- If GI effects, give with food
