Anti-Lipemics - General Flashcards
1
Q
CAD modifiable factors
A
- Gout (increased uric acid)
- Cigarette smoking
- Sedentary lifestyle
- High stress levels
- Hypertension
- Obesity
- Diabetes
- Untreated bacterial infections
2
Q
CAD non-modifiable factors
A
- Genetics
- Age
- Gender
3
Q
Lipoproteins
A
- Produced in the liver
- Low-density lipoproteins (LDL’s): tightly packed cholesterol, triglycerides, and lipids (BAD CHOLESTEROL)
- High-density lipoproteins (HDL’s): Loosely packed lipids
4
Q
Cholesterol
A
- Necessary for normal function
- Obtained through diet and fat metabolism/biotransformation
- Body CAN make enough cholesterol
- HMG-CoA responsible for cellular synthesis
5
Q
Hyperlipidemia
A
Increased levels of lipids in the blood
6
Q
Hyperlipidemia: Causes
A
- Excess dietary intake
- Genetic alterations in fat metabolism: Hypercholesterolemia, hypertriglyceridemia, alterations in LDL and HDL concentrations
7
Q
Other lipid lowering agents
A
- Fibrates: Lower triglycerides and LDL
- Vitamin B: Lowers triglycerides and LDL
- Omega-3 Fatty acids
8
Q
Fibrates
A
- Fenofibrate
- Gemfibrozil
- Fenofibric acid
9
Q
Vitamin B3
A
-Niacin
