Loop Diuretics Flashcards

1
Q

Medications

A

“-ide”

  • Bumetanide
  • Furosemide
  • Torsemide
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2
Q

Action

A
  • Blocks the chloride pump which blocks sodium and chloride reabsorption into circulation
  • Large amount of Na and Cl rich urine is excreted
  • Powerful diuretic
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3
Q

Indications

A
  • Acute HF
  • Acute pulmonary edema
  • Edema r/t CHF, renal, or liver disease
  • HTN
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4
Q

Contraindications

A
  • Allergy
  • Electrolyte depletion
  • Anuria/Severe renal failure
  • Hepatic coma
  • Pregnancy/lactation
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5
Q

Cautions

A
  • SLE
  • Hyperglycemia
  • Gout
  • Children under 18 y/o
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6
Q

Adverse effects

A
  • Hypokalemia/hypocalcemia
  • Hyperglycemia
  • Ototoxicity
  • Hypotension and dizziness
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7
Q

Drug-Drug interactions

A
  • Aminoglycosides or cisplatin: increased risk of ototoxicity
  • Anticoagulation: anticoagulant effects are increased
  • Indomethacin, ibuprofen, salicylates, or NSAIDs: decreased therapeutics effects of diuretic
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