Smell Flashcards
olfactory epithelium
used to detect odorants, mucus layer on epithelium traps odorants, axons of neurons in epithelium go straight to olfactory bulb
receptor cilia
terminated through diffusion, degradation, or cAMP feedback (stops G-protein signaling, leads to desensitization to smells in the evironment
coding for odorants
~350 types of receptors, each ORN only expresses one type of receptor, each receptor activated by multiple odorants, ORN are scattered randomly, kind of population coding
olfactory bulb and glomeruli
information from olfactory receptor cells in epithelium to to glomeruli in the olfactory bulb. information is sorted into specific glomeruli (ORNs with same receptor go to same glomerulus). Neighboring glomeruli detect similar chemical structures.
lateral inhibition
inhibitory neurons exist between neighboring glomeruli that detect similarly structured odorants. If one glomeruli is very activated it inhibits the other one
adult neurogenesis
neurons generated at surface of lateral ventricle and migrate to bulb. mostly interneurons are made.
olfactory pathway