Learning and Memory: Memory Systems Flashcards
Patient HM (Henry Molaison)
sever epilepsy, surgical lesions, identified damaged areas where seizures started and removed it (the medial temporal lobe including amygdala and hippocampus), lost all ability to make new memories
Memory type: declarative
things we can talk about, broken up into episodic (events) and semantic (facts)
Memory type: non-declarative
things that are hard to talk about, broken up into priming (facilitated processing of a stimulus the second time we see it), procedural (skills), and classical conditioning (learned association between two stimuli, broken into emotional and skeletal)
Memory type: working memory
temporary storage of information, limited capacity, require continuous rehersal
HM and motor skills
could learn new motor skills (procedural memories), mirror drawing task (number of errors decrease)
HM and timing
can remember some information but cannot remember a lot (relied on working memory) whereas controls could remember more over time by developing strategies for remembering
HM and priming
could do priming tasks, show subject series of words, take a break, ask subject to fill in chart and they subconsciously fill in the blanks with the words from the list
HM and classical conditioning
could be classically conditioned
Areas of the brain: declarative
medial temporal lobe (MTL), diencephalon (thalamus and hypothalamus), throughout cortex
Areas of the brain: non-declarative
priming: neocortex (just regions of cortex with 6 layers), procedural: striatum (putamen and caudate), emotional classical conditioning: amygdala, skeletal classical conditioning: cerebellum
Areas of the brain: working memory
prefrontal cortex
amnesia
retrograde: things in the past, anterograde: things in the future, HM helped identify differences between recent past and past memories
how does memory change over time?
consolidation: storing new memories into long term memory, requires protein synthesis, novel memories are more likely to be consolidated
neural basis of memories
engram: physical representation of memories
studying declarative memories
spatial memory: mental representation of the environment and locations in it
place cell: a neuron in the hippocampus that fires APs only when is in a certain region of space (not topographically arranged)
spatial memory test: Morris water maze