Resting membrane potential

Question 1

two forces acting on ions:

Answer 1

diffusional forces (chemical gradient), electrical forces

Question 2

concentrations of Cl-, K+ and Na+

Answer 2

inside: low cl, high k, low na. outside: high cl, low k, high na

Question 3

nerst equation

Answer 3

Eion= (61.54 mV/z) log ([ion]o/[ion]i)

Question 4

equilibrium potential

Answer 4

the membrane potential at which the diffusional forces and electrical forces are balanced

Question 5

driving force

Answer 5

DFion = Vm - Eion
negative DF: wants to make cell more positive (positive ions move in and negative ions move out)
positive DF: wants to make cell more negative (positive ions move out and negative ions move in)

Question 6

Na+/K+ pump

Answer 6

establishes the concentration gradient, 3 Na+ and 2 K+

Question 7

Goldman’s equation

Answer 7

Vm = 61.54 mV log (Pk[K+]o + Pna[na+]o)/ (Pk[K+]i + Pna[na+]i)