Movement Spinal Control Flashcards
muscle contraction
controls all movement, flexors: create smaller joint angles, extensors: create larger joint angles, relaxation: lack of contraction
alpha motor neuron
cells in ventral root of spinal cord, cause the contraction of muscles
rostral- caudal organization
size of ventral horns corresponds to amount of muslce in the area, amount of white matter corresponds to amount of axons in the area (how faw away from brain)
dorsal-ventral and medial-lateral organization
strucutre of muscle fiber
many myofibrils make up a fiber, T-tubules contain extra-cellular solution, sarcoplsmic reciculm is like the ER, sarcolema is the plasma membrane
getting ready for muscle fiber contraction
muscle has Ach receptors (ionotropic, Erev ~ 8), Ach depolarizes mucle cells producing an AP, AP goes on sarcolema and into T-tubules, at regions where T-tubules are close to sarcoplasmic reticulum there are Ca2+ channels, depolarization opens channels allowing Ca2+ to go out of sarcoplasmic reticulum and into cytosol
muscle fiber contraction
at rest, tropomyosin blocks myosin (thick filament) binding sites on actin (thin filament). when troponin binds Ca2+, tropomyosin moves away to expose myosin binding site so thick filament can move along think filament ot produce a contraction, myosin disengages from actin using ATP, if Ca2+ still present, mysoin continues moving, Ach is degraded by acetylcolinesterase, receptors close, sorcolema returns to rest, Ca2+ is acively pumoed back into sarcoplasmic reticulum
The NMJ is very reliable because
there is a lot of Ach per vesicle and a high denisty of Ach receptors on the muscle
inputs to aplha motor neurons
interneurons: project very locally, in grey matter of spine
muscle spindles: type pf proprioceptor (Ia), directly synapses onto aplha motor neurons
upper motor neurons: help us conciously control movement
Reflexes
automatic responses to stimuli, circitry is in spinal cord (doesn’t go to brain)
Myotatic reflex purpose
contraction of a muscle fiber in response to muscle stretch, uses propioceptor input
ex. if a box is heaver than we think it is our muscles are streched and we automatically contract muscles more so we are able to hold it up
reverse myotatic reflex purpose
inhibition of muscle contraction in response to tension in the tendons, uses propioceptor input
ex. box is way heavier than we think, we feel tension in tendons which connect muscle to bone (can’t risk damage here), muscles give up and drop it
flexor/crossed extensor reflex purpose
removes limb from noxious stimulus (flexor) and maintains balance (crossed extensor), nociceptor input
myotatic reflex mechanics
gamma motor neurons and muscle spindles
gamma motor neurons send signal to intrafusal fibers so the muscle spindles stay online with the extrafusal fibers (which do the contraction) and can detect stretch