Skin pathology III

Question 1

What causes a dermoid cyst

Answer 1

Incomplete separation of ectoderm and neuroectoderm during embryogenesis

Question 2

What kind of cyst is a dilated pore of winer?

Answer 2

consisting of a large pore connecting with the epidermis
and irregular hyperplasia of the wall.

Question 3

What is a sebaceous duct cyst?

Answer 3

cyst in the eye surrounded by hyperplastic sebaceous glands

Question 4

What is a hamartomas?

Answer 4

benign growth that contains the same type of
cells that are normally found in the tissue where they grow.

Question 5

What is a follicular hamartomas?

Answer 5

Cluster of large anagen hair follicles that extend more deeply than adjacent normal follicles

Question 6

What is a fibroadnexal haematoma?

Answer 6

aggregates of distorted, variably inflamed
pilosebaceous units surrounded by dense collagen and
lacking a connection to the skin surface

Question 7

What is a collagenous hamartoma?

Answer 7

a nodular accumulation of mature dermal collagen

Question 8

What is a vascular hamartoma?

Answer 8

proliferation of small vessels,
may be misdiagnosed as hemangiosarcoma

Question 9

What is a cutaneous horn?

Answer 9

a horn-like projection of the stratum corneum

Question 10

What is glandular hyperplasia?

Answer 10

nodular accumulation of hyperplastic glands

Question 11

What is a Fibroepithelial polyp also known as?

Answer 11

a skin tag

(mass of collagen covered in epidermis)

Question 12

What causes a virally-induced papilloma?

Answer 12

papillomavirus in young/ immunodepressed animals

Question 13

What is an equine sarcoid?

Answer 13

dermal proliferation with a pattern of fibroblasts caused by bovine papillomavirus

Question 14

What is actinic keratosis?

Answer 14

epidermal hyperplasia and dysplasia of basal cell layer, increased mitoses.

Question 15

What is an in-situ carcinoma?

Answer 15

neoplastic transformation of keratinocytes
does not invade the basement membrane.

Question 16

What is a squamous cell carcinoma?

Answer 16

Dermal invasion of neoplastic keratinocytes with mitotic figures all levels of epidermis

Question 17

What parts of the body does the squamous carcinoma usually effect?

Answer 17

Typically affect the sparsely haired and non-pigmented skin of ears and face (feline), penis and
prepuce (equine), conjunctiva (bovine and equine)

Question 18

Where do tumours with adnexal differentiation arise from?

Answer 18

they arise from sebaceous or modified sebaceous glands

Question 19

What breeds are genetically predisposed to dermoid cysts?

Answer 19

Rhodesian Ridgeback, Boxer

Question 20

Where do follicular cysts originate from?

Answer 20

They originate from different portions of the hair follicle

Question 21

What is a koliocyte?

Answer 21

swollen keratinocyte with a perinuclear halo

Question 22

How may a squamous cell carcinoma arise?

Answer 22

UV-Induced mutation p53 -> pyrimidine dimers -> nucleotide repair pathway is overwhelmed
may be associated with a papilloma virus infection

Question 23

What is a melanocytoma?

Answer 23

benign, circumscribed mass of heavily pigmented epithelial cells along the dermo-epidermal junction