Skeletal Bones 6 Bone Histology Flashcards
Bone is a type of?
Connective tissue that contains cells and matrix
Define Osteogenic Cells:
Bone Stem Cells that create other bone cells such as Osteoblasts + Osteocytes
Location: Endosteum + Periosteum
Define Osteoblasts:
Bone-forming cells, form new bone matrix
Location: Endosteum + Periosteum
Define Osteoclasts:
Bone Dissolving Cells
Resorb + remove bone matrix
Location: Endosteum + Periosteum
Define Osteocytes:
Mature Bone Cells that develop from Osteoblasts that have been surrounded by bone matrix
Function: Maintain bone matrix
Location: Compact +Spongy Bone
Define Bone Matrix:
Calcified Matrix made up of Collagen fibers + Calcium Phosphate
Define Collagen Fibers:
The main organic component of bone
Protein provides strength + flexibility
w/out Collagen fibers bones will be too brittle
Define Calcium Phosphate:
Main inorganic mineral
Function: acts like hard cement to hold up bones and prevent bones from sagging
Define Bone Homeostasis:
The Maintenance of Bone matrix
- Osteocytes recycle collagen + Calcium phosphate
- Osteocytes release chemicals to dissolve adjacent matrix + release the minerals into bloodstream
- Osteocytes rebuild the Matrix by depositing Calcium Phosphate