Serotonin Agonists and Antagonists Flashcards

1
Q

When do you give 5HT

A

Anaphylaxis

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2
Q

5HT 1D/1B agonist

A

Sumatriptan (prototype)

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3
Q

5HT 4 agonist

A

Metoclopromide

Cisapride

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4
Q

5HT 2 antagonist

A

Cyproheptadine

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5
Q

What is not used due to serious cardio effects

A

Cisapride

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6
Q

What do you use for hyperprolacinemia

A

Bromocriptine
Cabergoline
(DA agonists)

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7
Q

5HT 3 antagonist

A

Ondasetron

Granisetron

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8
Q

Ergot alkaloids (antagonist)

A
Ergotamine
Dihydroergotamine	
Bromocriptine
Cabergoline
Ergonovine	
Methylergonovine
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9
Q

Which promote and organize gut motility

A

Metoclopromide

Cisapride

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10
Q

What receptor does Cyproheptadine also block

A

H1

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11
Q

Which are powerful antiemetics

A

Ondasetron

Granisetron

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12
Q

What else do ergot alkaloids act on

A

Alpha
DA in CNS
Very non-selective

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13
Q

Pt has gastroparesis and emesis

A

Metoclopromide

Cisapride

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14
Q

Carcinoid syndrome Tx

A

Cyproheptadine

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15
Q

Used in allergic/vasomotor rhinitis

A

Cyproheptadine

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16
Q

Treat N/V in cancer therapy

A

Ondasetron

Granisetron

17
Q

2nd line for migraines

A

Ergotamine

Dihydroergotamine

18
Q

Used in post-partum hemorrhage (IM)

A

Ergonovine

Methylergonovine

19
Q

Provoke/Dx of variant angina

A

Ergonovine

20
Q

DOC acute severe migraines

A

Sumatriptan