Serotonin Agonists and Antagonists Flashcards
When do you give 5HT
Anaphylaxis
5HT 1D/1B agonist
Sumatriptan (prototype)
5HT 4 agonist
Metoclopromide
Cisapride
5HT 2 antagonist
Cyproheptadine
What is not used due to serious cardio effects
Cisapride
What do you use for hyperprolacinemia
Bromocriptine
Cabergoline
(DA agonists)
5HT 3 antagonist
Ondasetron
Granisetron
Ergot alkaloids (antagonist)
Ergotamine Dihydroergotamine Bromocriptine Cabergoline Ergonovine Methylergonovine
Which promote and organize gut motility
Metoclopromide
Cisapride
What receptor does Cyproheptadine also block
H1
Which are powerful antiemetics
Ondasetron
Granisetron
What else do ergot alkaloids act on
Alpha
DA in CNS
Very non-selective
Pt has gastroparesis and emesis
Metoclopromide
Cisapride
Carcinoid syndrome Tx
Cyproheptadine
Used in allergic/vasomotor rhinitis
Cyproheptadine